Saturated fats harm health
Diet has a major impact on our health. For example, experts advise against the regular consumption of saturated fats, as these affect the general life expectancy. The consumption of such fats is often associated with the worldwide spread of obesity, obesity and type 2 diabetes. Researchers have now discovered that you do not have to consume too much to damage your health. Even a single high-fat meal can affect your metabolism.
study reveals the earliest changes in liver metabolism
Scientists at the German Diabetes Center( DDZ) and the Helmholtz Zentrum München have found that even the single intake of a larger amount of palm oil, the sensitivity of the body forInsulin decreases as well as causes increased fat deposits and changes in the energy metabolism of the liver.
According to a statement from the Helmholtz Center, the study results provide information about the earliest changes in liver metabolism that can lead to long-term fatty liver disease in overweight and type 2 diabetes.
A single high-fat meal may cause insulin resistance
Researchers at the German Center for Diabetes Research( DZD), in collaboration with Portuguese colleagues, published a study on healthy, lean men who randomly chose a flavored palm oil drink in the journal "Journal of Clinical Investigation"and another time got a glass of clear water.
According to the information, the palm oil drink contained a similar amount of saturated fat as two cheeseburgers with bacon and a large portion of French fries or like two salami pizzas.
The experts showed that this single high-fat meal is sufficient to reduce insulin action, thus producing insulin resistance and increasing the fat content of the liver.
In addition, changes in the energy balance of the liver could be detected.
The observed metabolic changes are similar to the changes seen in people with type 2 diabetes or non-alcoholic fatty liver disease( NAFLD).
"NAFLD is the most common liver disease in the developed world and associated with obesity, the so-called" metabolic syndrome ", and increased risk of type 2 diabetes. In addition, NAFLD can lead to severe liver damage in advanced stages, "the DDZ said.
Effects on the Liver of Healthy People
"It was surprising that a single dose of palm oil in healthy people has such a fast and direct effect on the liver and by the amount of fat already administered an insulin resistance is triggered," said Prof. Dr. med. Michael Roden, Scientific Director and Board Member of DDZ and DZD.
Already in the past, experts have warned about the risks of palm oil in food, pointing out that it should be replaced altogether.
Palm oil affects muscle, liver and adipose tissue
Researchers have shown that taking palm oil affects muscle, liver and adipose tissue in their metabolic activity.
Induced insulin resistance, for example, leads to increased liver re-growth and concomitant decreased sugar uptake in skeletal muscle, a mechanism that raises blood sugar levels in type 2 diabetes and its precursors.
In addition, the insulin resistance of adipose tissue causes an increased release of fats into the bloodstream, which in turn further promote insulin resistance.
The increased availability of fat results in an increased workload of the mitochondria, which in the long term can overwhelm these cellular power plants and contribute to the development of liver disease.
The team of scientists suspects that healthy people can easily manage the immediate effects of high-fat foods on their metabolism, depending on the predisposition of the genes. However, the long-term consequences for regular eaters of such high-fat meals could be problematic.(ad)
You do not necessarily have to resort to fries, cheeseburgers and pizza every day to increase your diabetes risk. A single high-fat meal is enough to cause insulin resistance and increase the fat content of the liver, according to a new study.